Slide No. 22  •  Marketing Meeting  •  05.04.04
Contribution de la GPP à la charge glucosée1
1. Monnier L, Lapinski H, Colette C. Contributions of fasting and postprandial plasma glucose increments
to the overall diurnal hyperglycaemia of type 2 diabetic patients. Diabetes Care 2003;26.
Zone de Texte: Contribution (%)
Contribution (%)
(<7.3) (7.3-8.4) (8.5-9.2) (9.3-10.2)   (>10.2)
HbA1c %
>70%
Postprandial glucose excursions make a significant contribution to the overall daily hyperglycaemia of type 2 diabetic patients.
The exact contribution appears to vary according to the degree of glycaemic control.
According to one recent study, in well-controlled patients (HbA1c <7.3) postprandial hyperglycaemia contributed 70% of the overall diurnal hyperglycaemia.1
 In poorly controlled patients (HbA1c >10.2) postprandial hyperglycaemia contributed 30% of overall hyperglycaemia.1
Therefore:
PPG makes a major contribution to overall glycaemic control (up to 70%)
The greatest contribution is in fairly or moderately well-controlled patients
A window of opportunity exists, to target PPG early in disease progression.


1. Monnier L, Lapinski H, Colette C. Contributions of fasting and postprandial plasma glucose increments to the overall diurnal hyperglycaemia of type 2 diabetic patients. Diabetes Care 2003;26.