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Odonto-Stomatologie tropicale

Publié en Français dans Odonto-Stomatologie tropicale Volume 22 - Mars 1999 pages 23-28

Diagnosis of oral premalignant and malignant lesions using cytomorphometry Article Open access

Auteurs : T. RAMAESH, B.R.R.N. MENDIS, N. RATNATUNGA, R.O. THATTIL - Sri Lanka

Abstract
Diagnosis of oral premalignant and malignant lesions using cytomorphometry

In this study cytomorphometry has been applied to smears collected from the buccal mucosa. Normal cells and the cells collected from lesions with no dysplasia, dysplasia and squamous. cell carcinoma were differentiated using discriminant analysis based on nuclear and cell diameter values. Cytomorphometrically the dysplastic and malignant cells were well discriminated from the normal cells. A sensitivity of 89%, specificity of 89.7%, positive predictive value of 80% and negative predictive value of 94.4% were obtained when comparing non-dysplastic lesions with dysplastic lesions.

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